Strictly speaking, depending on party size, campaign level, preparation and DM willingness you could potentially have vast arrays of enemies leaving your reach and provoking opportunity attacks in one round via feats, spells, class abilities, glyphs of warding, and many, many other exploits. Now all we need is a bunch of enemies to provoke opportunity attacks from our ranger. With this, you can get more than two Colossus Slayer strikes per round if you can get multiple enemies to provoke opportunity attacks. Colossus Slayer allows you to inflict extra damage as long as your enemy has taken at least 1 hp of damage, once per turn. More than 5 feet while within your reach. Use your reaction to make a melee attack against a creature that moves While in your defensive stance, youĬan make opportunity attacks without using your reaction, and you can As a bonus action, you can enter a defensive stance that lasts

You excel at defending narrow passages, doorways, and other tight Unfortunately, if you have a level 20 character and do this, then the god of action economy will appear in real life and smite you.īut there is an Unearthed Arcana fighting style called Tunnel Fighter (from UA: Light, Dark, Underdark!), which can trigger the extra damage from Colossus Slayer many, many more times in a single round without incurring divine intervention (emphasis mine): The easiest and stupidest way to get more damage out of Colossus Slayer is to be a multiclassed level 17 Wizard / level 3 Ranger and use time stop to get multiple turns in one round. But an extra 2d8 per round doesn't really feel like it's going to kill a colossus, does it? As per the correct answer you can get a second activation during another characters turn via attack of opportunity (or via a Battle Master fighter's Commander's Strike maneuver). So if you attack and hit once in your turn you can't any more activation in that turn (short of wish shenanigans). So the problem is that Colossus Slayer is limited per turn. To add to NautArch's answer, the answer to your question is yes - Colossus Slayer does work with opportunity attacks - but there are some interesting edge cases where you can do the extra damage from Colossus Slayer three (or more) times in a round.

Colossus slayer 5e